In the world of cosmetic treatments, neuromodulators have become a popular choice for reducing the appearance of fine lines and wrinkles. Among the most well-known Neurotoxins are Botox, Jeuveau, Dysport, Xeomin, and the newer entry, Daxxify. While all of these products serve a similar purpose, they have distinct characteristics that may influence a patient’s choice. Here’s a closer look at what sets them apart.

Botox vs. Jeuveau vs. Dysport vs. Xeomin vs. Daxxify: A Comparison

Botox

• Overview: Botox, produced by Allergan, is perhaps the most recognized name in neuromodulators. It was the first to be approved by the FDA for cosmetic use in 2002.
• Composition: Botox is made from onabotulinumtoxinA, a purified form of botulinum toxin type A.
• Onset and Duration: The effects of Botox typically begin to appear within 3 to 5 days after injection, with full results visible within 1 to 2 weeks. The results generally last about 3 to 4 months.
• Usage: Botox is widely used for treating forehead lines, crow’s feet, and frown lines between the eyebrows.

Jeuveau

• Overview: Jeuveau, developed by Evolus, is a newer player in the aesthetic market, gaining FDA approval in 2019. It is often referred to as “Newtox.”
• Composition: Similar to Botox, Jeuveau is composed of prabotulinumtoxinA.
• Onset and Duration: Jeuveau typically has a similar onset and duration of effect as Botox, with results appearing in about 3 to 5 days and lasting approximately 3 to 4 months.
• Usage: Primarily used for treating glabellar lines (frown lines), Jeuveau is marketed with a focus on millennial consumers seeking preventative treatments.

Dysport

• Overview: Dysport, manufactured by Ipsen, was approved by the FDA in 2009. It is often chosen for its quick onset and natural-looking results.
• Composition: Dysport is made from abobotulinumtoxinA.
• Onset and Duration: Dysport tends to act faster than Botox, with results often visible within 2 to 3 days. The effects can last 3 to 4 months, similar to Botox.
• Usage: Dysport is favored for treating larger areas like the forehead due to its ability to spread more easily than other neuromodulators.

Xeomin

• Overview: Xeomin, developed by Merz Pharmaceuticals, was approved by the FDA in 2010. It is known for being a “naked” injectable.
• Composition: Xeomin is made from incobotulinumtoxinA and is unique because it does not contain any accessory proteins.
• Onset and Duration: Results from Xeomin can appear within 3 to 4 days and last around 3 to 4 months.
• Usage: Xeomin is often recommended for patients who have developed resistance to other botulinum toxin products due to its pure formulation.

Daxxify

• Overview: Daxxify is the latest addition to the neuromodulator family, having received FDA approval in 2022. It is notable for its extended duration of effect.
• Composition: Daxxify is formulated with daxibotulinumtoxinA-lanm, and it includes a proprietary peptide that prolongs its effects.
• Onset and Duration: While onset is comparable to other neuromodulators, the effects of Daxxify can last up to 6 months or longer, making it a standout choice for those seeking longer-lasting results.
• Usage: Daxxify is used for treating moderate to severe frown lines, with ongoing studies exploring its efficacy in other areas.

Conclusion

While Botox, Jeuveau, Dysport, Xeomin, and Daxxify all serve the primary function of reducing facial wrinkles, they each have unique properties that might make one more suitable than another depending on individual preferences and needs. Factors such as onset time, duration of effect, composition, and specific treatment areas should be considered when choosing the right neuromodulator. Consulting with a qualified healthcare provider Serenity Med Spa of Georgia can help determine the best choice based on personal aesthetic goals and medical history.